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Meniscal Transplants in Knee Arthritis to Avoid Joint Replacement
By Dr. Paul Anderson M.D. Sports Medicine and Pain Expert There is an orthopedic group out of San Francisco performing meniscal transplants to avoid early knee replacements. This is a radical idea but the early studies results are promising.
But before you consider surgery, my suggestions is to try natural anti-inflammatories, with knee cartilage growing nutrients and knee exercises to avoid any kind of knee surgery.
Here's the study. Meniscus allograft survival in patients with moderate to severe unicompartmental knee arthritis: a 2- to 7-year follow-up.
Stone KR, Walgenbach AW, Turek TJ, Freyer A, Hill MD. Abstract
PURPOSE:We present meniscus allograft survival data at least 2 years from surgery for 45 patients (47 allografts) with significant arthrosis to determine if the meniscus can survive in an arthritic joint. Type of Study: Prospective, longitudinal survival study.
METHODS:Data were collected for 31 men and 14 women, mean age 48 years (range, 14 to 69 years), with preoperative evidence of significant arthrosis and an Outerbridge classification greater than II. Failure is established by previous studies as allograft removal. No patient was lost to follow-up.
RESULTS:The success rate was 42 of 47 allografts (89.4%) with a mean failure time of 4.4 years as assessed by Kaplan-Meier survival analysis. Statistical power is greater than 0.9, with alpha = 0.05 and N = 47. There was significant mean improvement in preoperative versus postoperative self-reported measures of pain, activity, and functioning, with P = .001, P = .004, and P = .001, respectively, as assessed by a Wilcoxon rank-sum test with P = .05.
CONCLUSIONS:Meniscus allografts can survive in a joint with arthrosis, challenging the contraindications of age and arthrosis severity. These results compare favorably with those in previous reports of meniscus allograft survival in patients without arthrosis.